Is this a genuine Brother replacement cartridge, if not you may find that it is not recognised by your MFC. Also worth a try is removing and reinstalling the new cartridge ensuring all protective packaging is removed. Also remove and reinstall the Drum unit as Brother actually recommend this as part of a new toner install
http://www.brother-usa.com/ModelDocuments/Consumer/Users%20Manual/UM_MFC_7420_7820N_EN_1156.PDF
1. With unit powered On, open the front cover.
2. Press the "Options" key. Display will show "Replace Drum?"
3. Press "Start" key.
4. Press 1,0 .
5. Display will show "Accepted" for approximately 2 seconds. Then display will change to "Cover Open".
6. Close cover and see if Toner Life End error message has gone.
Good Luck and Thank You for using Fixya.
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