Vertical red lines on screen

It is normally the disc that either is scratched, has dust on it or is dirty.

You can clean the disc with warm water if it is dirty, that won't damage it, but don't use boiling water, that would be crossing the line.

If the game is scratched, you might check your nearest GameStop, they might have this disc fixer, or whatever they call it. They have it here in Norway, so I guess they have it most places around the world. :)

erm this might be a firmware issue i suggest if your still under warrenty contact xbl customer support and they will reflash the firmware on the cd drive

U freeze video games 10-20 mins in video game alot of time.Never pause or freeze any kinds of video image in Plasma tv.It very easy cause to burn in Plasma tv problems alots.

try and save the game to your Xbox360 harddrive(HDD) and then run it off that?

i have no clue im a big fan of saints row i can tell you any ather thing about the game

Well the disc driver obviously works on most of your games except saints row 2. Saints row 2 is in mint condition well i have this problem too with my 360 it reads some games and it doesn't read my other ones well theirs a few ways one is by leaving the game inside of the console and shut it down wait like 5 seconds and turn it back on.
Another is to make sure the laser its self doesn't have dust on it.
And when you put in a disc listen to it as it spins if makes any weird scratching noise its probably the laser hitting the disc a lot of 360s disc have been getting scratched recently due to the fact in microsoft's original design of the disc drive the laser keeps on hitting the disc and scratching it so if thats the case you have to replace the disc drive.
If solutions don't help let me know i might be able to help you more.

try to change your video settings becouse that might be a big plart of it whean i was playing saintsrow2 that i downloaded for free i had the same problem exspt a bit further into the game i was getting a black screen the sound was still on but nothing was happeing and even a few times it hade just a crack in the middile like i shot my monitor with a bb gun

maybe you should try different games? see if those different games freeze, if so, then it might be your blu-ray player in your ps3, or your ps3 might be overheating. my games froze at certain points because my ps3 was overheating, just try a few different games

heya clark...unfortunately your bluray laser has probably failed or is failing. the diode burns out quickly on these units. call sony they charge 150+tax+2-4week turnaround or send it to me. i can fix for 100..

1. Get 3 towels then switch your Xbox 360 on.
2. Wrap the Xbox 360 in the towels [Note - You must cover the WHOLE Xbox otherwise it won't work].
3. Leave your xbox for 25 mins in the towels.
4. When the 25 mins is over take off the towels of and let your Xbox 360 to cool for 20 minutes, enjoy fixed gaming for the next 4-7 days. Once you get a blank screen repeat this process.

[Why Overheat it?]
When overheating it you attempt to solder the dis-connected wires back to the motherboard.
I recommend getting it fixed instead.

[What does it Fix?]
This fixed the Red Ring of Death, and the Blank Screen of Death

[DANGER]
I do not take responsibility for this. This is mainly for those without warranty or money to repair.

The premise is to wrap the towel around the 360 and to let it heat up. This will weaken solder points and hopefully re-join broken connections. The problem with this method is that you have no control over what solder points are weakened and there is no way to prevent further damages caused by the heat. It is better to send a 360 in for repair with the three year warranty that MS put on the 360s, because if you try the towel method and then send it in for repairs, they will know by the solder points being misshapen and it will void your warranty forcing you to pay for the repairs.