What OS do you have? The drivers (supported OS versions) for the LiDe 80 are available here:
http://www.cusa.canon.com/cusa/support/consumer/scanners/canoscan_series/canoscan_lide_80#DriversAndSoftware . If you have Win7 64-bit, the Vista x64 driver doesn't work even in the compatibility mode.
If you want a work-around for the 64-bit OS, Win7 Pro and Ultimate allow you to download and install XP mode free. This takes two programs, Virtual PC and the XP mode, that you download from Microsoft and install. This will run a virtual computer under Win7 and you can install the scanner to the virtual computer. To share files with the real computer, you should store them on external media.
Alternatively for Win7x64, you can install any of the other Virtual computer programs (Parallels, VMWare, etc) with a licensed older version of Windows. Then do the same as above. Another option is a dual boot computer with the older licensed version of Windows with the scanner installed to the "machine" with the older OS. I don't see a Unix driver for this scanner so you need a valid copy of Windows.
I hope this helps.
Cindy Wells
(If you have Win7 x64, the only other options are 1) to try and get Canon to extend their drivers (since they do support Win7 32-bit) or 2) get a new scanner.)