Try increasing the latency. Depending on your computer, it may not be able to handle low latency levels. Latency is a measure of the delay between the time you make a sound and the time the computer records that sound. With the Mbox mini, the unit for latency is the number of samples the driver collects before sending them to an application as input. Lower latency can make recording easier and more accurate, but not all computer systems can operate at the lowest latencies without introducing noise.
Open the Mbox mini dialog and select the latency tab. experiment with higher latency levels and see if it goes away.
This is what the dialogue might look like.
another solution would be to try a different DAW. I had the same problem with my Fast Track Pro in ProToolsand it worked fin on Reaper, Garageband and Logic.
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