I don't have a Toshiba Laptop, or a computer for that matter, but I do have a Toshiba DVD/CD ROM drive that has been not functioning correctly lately.

Yes its possible. I have one too. Its frm LG slim portable DVD rom

Hello
First thing you do is to see what hard disc installed in your laptop. You can check that by checking it in your bios system. To check in your bios system first turn off your computer then press delete while your laptop is booting up. Then you will see if there is a hard disk detected in your lap top if there is a detected hard drive this means you have a problem in your windows installed in your lap top.
There is also a reason why those message appear if the first boot of your laptop is the CD/DVD ROM. Check you CD/DVD ROM if there a CD inside this may the first on to read while the laptop booting up. Remove the cd inside your CD/DVD ROM. Then restart your laptop. Check your hard disk connector it may have some loose contact thats why your laptop did not recognize the hard disc.
Hope this can help keep on touch with fixya. Hope to hear some testimonial from you. . .

is the toshiba portable drive compatible to other laptop like acer?

I searched for Toshiba CD-ROM drives and found only support references to products made about ten years ago. Toshiba shows only hard drives on its storage device products page. I could be wrong, but it appears Toshiba is not in the CD/ROM drive business anymore.

Is there a particular reason you must have a Toshiba brand CD-ROM? Any CD-ROM with the same interface type should work, if you can find a driver compatible with your operating system. If I recall correctly, Toshiba uses Sony optical drives in its laptop computers. (So far as I know Toshiba always used standard interfaces, so a proprietary drive should not be an issue.) The prices on CD-R and CD- R/W devices have come down considerably in the last several years, so you may want to consider one of those if your computer is fast enough to support reliable disc burning operations (800 MHz or better should suffice).

go to Dektop / My Computer
right click
u will c all the drives....i mean..... c: d: etc
locate ur CD/DVD rom drive,..letter...d: or e: etc..
select ur CD/DVD rom drive
right click and chose option Eject...
u r set...

sounds like your using cd burning software , you might want to try using nero, and try using the correct settings on the software your using now.

Seems like the DVD drive went bad.
My advice is try another DVD drive and install it on the same laptop. just to make sure the laptop is ok.

Please don;t forget to rate is this answer helps you in some way

dvd burners or rom drive have 2 lens inside, one for DVD read, the other for cd read. I see it often where one fails out in the drive but the other works. With one working fine and the other not, I would replace the drive. If still under warranty send it to manufacturer. If not do a search on Ebay for a replacement drive, or get a local laptop repair shop to do it for you.

open windows media player, go to file and look for the open disc and click your cd rom drive. it will automatically read the dvd inside your cd rom

make uninstall driver for CDW/DVD then re-boot.
Install the driver for CDW/DVD and use. It will fix your problem.

Thanks
Iqbal