2001 Acura MDX Center console is not working. No heater or AC and it won't light up.is there a fuse for the center column running the whole thing?

Fuses are under the steering wheel against the left side of the car.

honda pilot and acura mdx share a lot of the same parts. The rear blower motor resister is known to go out after a while.
http://www.acuraworld.com/forums/f8/mdx-back-seat-blower-doesnt-work-71111/

Either buy the honda part 80 bucks, or you can buy a resistor and fix it yourself for about 10 bucks. Details in the link above.

It's behind the rear ac controls. Just pull on it hard and you'll see the lil black box

Most likely cause is blower transistor under drivers side of center console cover u have to remove side cover it has a1 electrical connector and it twist to remove

Check this website - you find there fuse box diagram and description for Acura MDX (2004)

Acura MDX 2004 fuse box diagram Auto Genius

On this website you find fuse box diagram and description for Acura MDX (2001)

Acura MDX 2001 2002 fuse box diagram Auto Genius

Here's an excerpt from the 2002 Acura MDX 4WD 6cyl Repair guide for replacing what the reference manual calls the "control assembly" - its located under the console rear trim and may (or may not)
contain the blower resistor - my manual doesn't say - but this is the closest thing I could find for you. Every other blower resistor I've had to find was located close to the heater controls - and this
car seems to be no exception -- its heater controls are located in the console between the seats, rather than in the dash (as in Acura 2003-06 MDX models).

You may want to call your friendly Acura dealership ad speak to the parts department, to make sure where the blower resistor is located - or a visit to a dealership parts counter often (or
Advance Auto Parts is helpful too) ofen clarifies questions I have from Haynes manuals (the cheapest car repair guides).

All this assumes that you've correctly diagnosed your blower control problem -- as in "replace the blower resistor when the blower works only on the MAX/Highest setting."

-- begin excerpt from 2001-2 Acura 4wd 6cyl MDX Repair manual --
Control Assembly Removal & Installation

2001-02 Models

1. Remove the console rear trim. Refer to the accompanying illustration.
   
   

   Fig. Exploded view of the console rear trim
   

2. Remove the self-tapping screws and the rear heater-A/C control unit (A) from the console rear trim (B).

To install:

1. Install the control unit in the reverse order of removal. After installation, operate the control unit controls to see whether it works properly.
2. Run the self-diagnosis function to confirm that there are no problems in the system.
   
   

   Fig. Remove the self-tapping screws and the rear heater-A/C control unit (A) from the console rear trim (B)
   



--- end excerpt from 2001-2 Acura 4WD MDX 6cyl Repair Manual ---

Take a look at the shift lock. When you depress the brake is there an audible click heard coming from the center column? If not there could be a few possible problems. Either your brake pedal switch is defective(brake lights coming on?) the wiring to the shift lock is open or shorted, or the shift lock itself is defective. A quick fix is to remove the small plastic cover just right of the shifter that is the shift interlock manual release. Using a small pocket screwdriver depress the white plastic button and move the shifter.

On this website (link below) you find fuse box diagram and description for Acura MDX (2004)

Acura MDX 2004 fuse box diagram Auto Genius

I went to an Acura dealer to buy the transistor for the rear A/C unit. The service advisor told me that the problem with the front A/C was probably due to a defective front transistor / resistor. I bought that part too.

The front transistor is located next to the blower motor under the dash on the passenger's side. It is secured by three or four small bolts. The one on the bottom left is very close to the carpet and the most difficult to get off and put back on.

The rear transistor is located behind the carpeted trim panel on the center console (driver's side). The carpeted trim panel is secured by clips only - there are no screws, so remove it carefully starting at the side near the accellerator pedal. Once the panel has been removed, reach inside a small hole in the metal frame to access the rear transistor. It is removed by twisting it and pulling it out. The hole in the frame is small and you might find pliers helpful.

After replacing both parts, the front and rear A/C are working. Apparently these transistors are common failures. If the A/C is out in your Acura MDX and the fuse checks good, a new transistor will likely solve your problem.