Misfire in #4. changed wires and both ignition coil still runs rough

I really couldn't tell you without checking it out. But I would check the coil pack or dist.Cap or ignition control module and change the sparkplug wires.

It's probably the Sparkplug wires or one of the coils, depending what your car has.

Part 3 -How to Test the Ignition Module and Crank Sensor ...

easyautodiagnostics.com > Ford > 2.3L

Mar 1, 2012 - Spark plugs for cylinders #2 and #3 get spark at the exact same time. ...voltage -12 Volts) to both individual ignition coils within the coil pack. ... Ford Mustang or Ranger (or 2.3L Mazda B2300), this is what you'll need ... for this 'Switching Signal' at the coil pack... but you can also test this ... 1991, 1992, 1993.

How to Diagnose a Misfiring Cylinder (2.3L Ford Ranger ...

troubleshootmyvehicle.com > Ford > 2.3L

Apr 3, 2012 - Bad Fuel Injectors can cause a Misfire Condition. ... the ignition system on the 2.3L Ford Mustang or Ranger consists of 2 ignition coil packs, ...

2002 ranger misfire rough idle - Discussion on Topix

www.topix.com > Ford Ranger

Jul 27, 2007 - My truck is giving the code misfire in number 4 cyl. I replaced my spark plugs, Wires, Coil packs (both of them) and all my fuil ... three (3.0L v6) go bad, the fuel/air mixture gets messed up. Judged: 2. 2 ... My truck runs rough only at idle. ...code for ford ranger 2002, 2.3 5speed. truck runs like a champ but that ...

Extremely stumped! I need the best and brightest 1994 Ford ...

answers.edmunds.com > Edmunds Answers

hi , if you are sure the no. 6 cylinder is misfire then change the ignition coil if you are sure but if you are going to buy a new coil better buy all 6 coils and it will last longer if not after no.6 then no.5 or 4,3, until you change all of it .....for rough runs pls flush / change ATF every 20,000 km and change engine oil every 5,000 km , change the exhaust (o2) sensor it make a lot of different , resetting your throttle sensor and speed sensor , all the above must change it with nissan oem part and it not that expensive too.

What have you checked so far? What engine? Check spark plug for ware, cracks and carbon tracking. Check the ignition wires for damage and voltage leaks, this could be done by spraying the wires with soapy water. If the car runs rough or you see arching replace the wires. Check for spark and check the ignition coil and replace as needed.if you still having problems you may have to check the injector or perhaps do a compression test.

yes. Replace the ignition coil pack for #4 plug wire.

if all that is good then the only other two things it can be is a intake gasket or a head gasket

usually when it gets colder outside the car will misfire and run rough because the ignition module/coil pack goes bad and makes it misfire,youre gonna have to replace the coil and module,,its the black long piece that sits on top of the spark plugs,1 wire connector and 4 10mm bolts remove them and pull up hard to pop the plug boots off the spark plugs,then install the new parts and you should be ok

try a new crankshaft sensor not hard to change 2 bolts and a wire

Here is a list of possible causes. You should not drive the vehicle if the check engine light is flashing all the time, you can cause even more damage. It could pay to have a professional find the real cause.

Spark plugs that are incorrect for the application, cracked, improperly gaped or worn can cause the engine to misfire or run rough at all times.
An IC module that failed to correctly control the ignition coil(s) will cause the engine to misfire or run rough at all times.
Poor connections, broken wiring or wiring that has shorts to ground can cause the engine to misfire or run rough at all times. NOTE: Check connectors that might be pulled apart as the engine flexes or wires that short to ground as they pass near brackets or shorts to ground on the exhaust manifold.
Fuel injector(s) that are shorted, plugged or partially restricted can cause the engine to misfire or run rough at all times.
An ignition coil(s) that has low output, corrosion on the coil tower(s), is carbon tracked or arcs to ground will cause the engine to misfire or run rough at all times.
A PCM that failed to properly control the injector or ignition timing will cause the engine to misfire or run rough at all times.

have you changed the ignition wires? perhaps firing order crossed? if not coil pack or ignition wires faulty how do you know it is not "FIREING" on 1 & 4 have you tested it with a spark tester tool???