Nikon scanner was unable to find active device

SOURCE: "Nikon scan unable to find any active devices"

Try the following site:
http://support.nikontech.com/cgi-bin/nikonusa.cfg/php/enduser/std_alp.php?p_sid=eyilbI*i&p_lva=&p_li=&p_accessibility=0&p_redirect=&p_page=1&p_cv=1.185&p_pv=1.25&p_prods=25&p_cats=185&p_hidden_prods=&prod_lvl1=25&prod_lvl2=0&cat_lvl1=185&p_search_text=&srch_btn_submit=%C2%A0%C2%A0%C2%A0Search%C2%A0%C2%A0%C2%A0&p_new_search=1&p_search_type=answers.search_nl
It is a part of Nikon's official site. You can start from Nikon.com.

SOURCE: dell laptop wont recognize ls2000 scanner

The LS-2000 is a "legacy" device to XP and the Nikon software. It needs to be connected to a true SCSI bus adapter, and it's actually pretty finicky about which ones will work in XP. Sorry, you won't be able to use this with your laptop.

SOURCE: Nikon scan was unsable to find any active device

I may have a solution for the unrecognized film holder/clunking problem.  The fix is not for the faint of heart, but you can do it yourself and save a bunch of money.  The problem lies in the two rails inside the scanner that the film carrier rides on.  After unplugging you scanner, remove the 8 screws from the rear of the unit and slide the cover rearward about 3/4" and then lift it straight off.  Inside you will see two shiny machined rods running from front to back.  The problem is those two rods have dried up lubricant on them and the film carrier drags a bit during film carrier insertion and/or scans.  The easiest way I found to clean the rods is to remove the front cover (look for screws inside on each side), and then carefully slide those rods out (but NOT all the way) and wipe off what is exposed and then apply a little silicone lubricant to the rods (be very careful to not get any down into the lens area).  Then slide the rods back in and repeat for the portion that is exposed in the rear.  Carefully re-assemble everything and you should be all set.  This fix worked for me on an 8000ED that I purchased used on eBay.  Hope this helps someone.  Brian

SOURCE: nikon scan was unable to find any active devices

The LS2000 is older than XP and has some fairly tight requirements to work. The recommended SCSI adapter is an Adaptec 2906, and you will probably need to backrev the ASPI layer driver files to version 4.7 (available on adaptec.com site). You may need to boot in Safe Mode to remove the later versions of the ASPI files before you can install the 4.7 files. You will also need to update your Nikon Scan software to version 3.1.2, available online by googling "nikon scan 3.1.2".