Stops brewing, have to turn it off then on again

All coffee makers do this over time from calcium, lime, and mineral deposits building up inside the tubes and heating coil. Fill the reservoir with a 50/50 mixture of water and white vinegar and run a normal brew cycle, turning it off and on if necessary to completely empty the reservoir. Repeat this 2 or 3 times with fresh mixture of vinegar and water until it brews the reservoir empty without the need to cycle the power. Follow this procedure with plain water 2 or 3 times to clean the vinegar out. This should get it working like new again. It's best to use distilled water for brewing coffee as distilled water does not have the minerals that regular tap water has and therefore will not clog up the machine.

You could be correct in your assessment and if so, as long as the device is under warranty it needs to go back for servicing. If you open the chambers, the warranty is Void and the device a boat anchor.

There is no self clean button on mine, and I have done the above with vinegar and water......what next?

I know this sounds like a pain but it takes a while to get that silly light to stop.
If you have problems call the 1-800 number below.
Decalcifying your MR. COFFEE® Coffeemaker Minerals (calcium/limestone) found
in water will leave deposits in your coffeemaker and affect its performance. It's
recommended that you regularly remove these deposits using MR. COFFEE® Cleaner
or vinegar. MR. COFFEE® Cleaner is available at many retail stores or by calling the MR.
COFFEE® Consumer Service Department at 1-800-MR COFFEE (1-800-672-6333).
1. Follow package instructions to prepare one batch of MR. COFFEE® Cleaner. Pour the
mixture into the water reservoir. Before decalcifying, remove the water filtration disk
from the machine.
NOTE: 4 cups or 20 fl. oz. of undiluted, white household vinegar may be used as a
substitute for the cleaner.
2. Place an empty MR. COFFEE® 10-12 cup basket-style paper filter
or MR. COFFEE® permanent filter into the filter basket and slide
the brew basket in place.
3. Place the empty decanter back in the unit.
4. Press the CLEAN button until the CLEAN indicator light turns on
(Figure 9). For your convenience the cleaning cycle is automatic.
The entire cycle will take 45-60 minutes to complete.
During the cleaning your coffeemaker will:
a. Slow brew approx. 3 cups of cleaning solution.
b. Pause for 30 minutes (the CLEAN light will remain on to alert
you that the process is active).
c. After 30 minutes, your coffeemaker will brew the remainder of the cleaning
solution.
d. When complete, the CLEAN light will turn off and your coffeemaker will turn off.
5. Discard the cleaning solution and rinse the decanter thoroughly with clean water.
6. Fill the water reservoir with clean, fresh water.
7. Place the empty decanter back on the coffeemaker.
8. Remove and discard the paper filter used during the cleaning cycle. If a Mr. Coffee®
permanent filter was used during cleaning, remove it and rinse it thoroughly before
replacing it in the filter basket.
9. Begin brewing and allow the full brew cycle to complete.
10. Repeat steps 5 through 9 one more time.

A common problem that can occur with the Cuisinart coffee maker is it will stop brewing, even when there is water ready to be transformed into coffee. The machine still turns on and works like it should, but does not continue brewing an entire pot of coffee, and acts like it has finished brewing even when there is still water sitting in the bin. This type of problem is pretty common among various coffee makers, and usually occurs when there is a problem inside the machine.
One of the best ways to fix this problem is by flushing the coffee maker out with a vinegar solution, which can be made with equal parts of vinegar and water. It should be poured in the same place as the water that is ready to be brewed, and will help to clear out the machine and make it ready to start brewing again. This problem is usually caused by calcium building up within the machine, and the vinegar helps to clear out any blockage to help it start running smoothly again.

I use distilled white vinegar, but you can use specialized coffee cleaners with this model:

Descaling
Descaling 11
Descale your Tassimo machine every three months to keep it
operating at full potential.
1 Descaling products are widely available from stores selling coffeemakers and espresso
machines. Only use a product intended for descaling. Mix the descaling product
directly in the water container, following the instructions provided on the descaling
packaging. Replace the water container on the machine.
2 Place a large cup or mug on the cup stand, insert the cleaning disc, bar code down,
and close the brew mechanism. When the AUTO light illuminates, press and release
the start/stop button. The brew cycle will fill the machine with descaling solution. Empty
the cup and let the machine stand for 15 minutes.
3 Open the brew mechanism and close it again, leaving the cleaning disc in place.
When the AUTO light illuminates, press and release the start/stop button. When the
machine stops running, empty the cup, and let the machine stand for 15 minutes.
Repeat this step two more times for maximum descaling effectiveness. Discard the
remaining descaling agent from the water container, rinse it thoroughly and refill
with fresh, cold water.
4 Open and close the brew mechanism again, leaving the cleaning disc in place.
When the AUTO light illuminates, press and hold the start/stop button to flush water
through the machine. The MANUAL light will flash. When the cup is full, release the
start/stop button, empty the cup, and replace it on the cup stand.
5 Repeat step 4, flushing clean water through the machine in the same manner and
emptying the cup as it fills. To ensure that all the descaling solution is completely rinsed
away, flush two full water containers through the machine before using it again.

Let a half caraffe worth of distilled white vinegar sit in the water reservoir for about an hour. After the hour, turn the coffeemaker on and let it brew the vinegar until a small amount of vinegar appears in the caraffe. turn the coffeemaker off and let it sit for an additional 20 minutes. Then turn the coffeemaker back on and let it brew the rest of the vinegar. Then run a full caraffe of plain water to flush the vinegar out. If the self-clean light remians on - unplug the coffeemaker for 20 minutes or longer - if you unplug it for any less than 15 minutes, the coffeemaker will not reset itself. You should be good after that - as long as you do some sort of vinegar/water cleaning once a month henceforth.

-Tha Mp3 Doctor

Try cleaning it with pure vinegar. 3-4 times just keep running it through the machine.

Could be electrical, but I would unplug for 20 minutes or longer and then clean with vinegar/water soltuion (2 cups vinegar, 2 cups water).
-Tha Mp3 Doctor

According to the manual for IS series Mr. Coffee for programmable models:
1. Prepare one batch of Mr. Coffee coffeemaker cleaner. Pour the mixture into the water reservoir. Remove the water filtration disk from the machine.
4 cups or 20 oz. of undiluted, white household vinegar may be used as a substitute for the cleaner.
2. Place an empty paper filter or permanent filter into the filter basket and close.
3. Place the empty decanter back in the unit, centered on the warmer plate.
4. Press SELECT button until the red CLEAN indicator light is illuminated. For your convenience the cleaning cycle is automatic. The entire cycle will take 45-60 min to complete. During the cleaning your coffeemaker will:

• Slow brew approx. 3 cups of cleaning solution.
• Pause for 30 min (the CLEAN light will remain on to alert you that the process is active). At the end of the pause period your coffeemaker will beep.
• After 30 mins your coffeemaker will brew the remainder of the cleaning solution.
• When complete, the CLEAN light will turn off and your coffeemaker will automatically beep and shut off.

5.Discard the cleaning solution and rinse the decanter thoroughly with clean water.
6. Fill the water reservoir with clean fresh water.
7. Place the empty decanter back on the coffeemaker, centered on the warmer plate.
8. Remove and discard the filter used during the cleaning cycle and replace it with a fresh paper filter. If a permanent filter was used during cleaning, remove it and rinse it thoroughly before replacing it in the filter basket.
9.Begin brewing and allow the full brew cycle to complete.
Repeat steps 6-9 one more time.