Did you install the full software (if available for your OS) before connecting the cables? Were you trying to launch the scan from the computer or the scanner? The scanner buttons will not work unless the full software is installed and the monitor program is running.
If you installed the generic OS driver, uninstall it and then unplug the data cable. Then download and install the software from
http://h10025.www1.hp.com/ewfrf/wc/softwareCategory?lc=en&dlc=en&cc=us&product=1153481& . Select your OS and click Next then click on Drivers. Start scans from the computer first. (HP Solution Center has destination buttons that need to be set before the buttons on the scanner can work. Once you scan from the computer, you will have a better idea of the settings you should use as defaults for the buttons.)
Try connecting the printer directly to the computer, if you use a USB hub or print server. Also try a new USB cable. The scanner requires bi-directional communication and thus can fail even if the printer works. Your cable should be 6' or less in length.
WinXP, Vista and Win7 have options for scanning without the HP software. However, they do not work with the scanner buttons. Launch Paint (Start > All Programs > Accessories > Paint) and select File > Import from Camera or Scanner > From Scanner in any of the listed OS versions. Vista and Win7 also include Windows Fax and Scan (New Scan). Vista has included Photo Gallery that also can acquire Scans (this is available for Win7 as part of the Windows Live package download).
I hope this helps.
Cindy Wells
(additional information can be obtained here:
http://h10025.www1.hp.com/ewfrf/wc/product?cc=us&lc=en&dlc=en&product=1153481 )
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