I cannot send mail on my MacBook Pro (Intel) using OS X's Mail program at home using my 2wire; it works at the office on Cable. What's wrong with my settings and is it software or hardware?

You may be using the wrong SMTP address for the Outgoing mail server address for your email service.

If you are not sure what your SMTP Outgoing Mail Server address is, then you can reference this link
below, to locate the Outgoing mail server address of your current email service provider

Link: POP & SMTP Email Server Addresses
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In regards to checking your mail settings in Mac OS X Mail you will need to perform these few steps:

*Launch Mail
• Click on Mail name and select Preferences from
the drop down menu.
• Now select the Account tab.
• Locate your affected email account from the side
bar and from Account Information, make sure
your Outgoing mail server address is correct.


I am using a .Mac account as an example,
but the same principal applies.

Now if you do find that the Outgoing mail server address for your email service is correct, then the issue may be with the SMTP server for your email service.

One way to determine SMTP functionality however, is to go online and use the web mail page for your email account and send out a test email.
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I would also recommend you make sure your Macbook Pro also has the most current version update.

Apple usually has bug fixes in each of their version updates for the Mac OS X Mail application, as well as other built in Mac OS X applications.

If you are still unable to send outgoing mail, contact your service provider to get more assistance and have them check your SMTP server address, authentication and connection with their Outgoing Mail servers.

Regards,

-Mactechtrainer