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If your keyboard and mouse are wired with USB port plugs then you could have either a faulty cord or USB ports in your system. Try using the keyboards on another PC and see what happens. Also you cannot connect a keyboard and mouse after the system has booted into windows and expect it to work. Either way your system will think nothing is attached until you reboot. Try this out and see what happens.
Try booting your computer from CD ROM with the OS CD/DVD already inserted and when prompted just try repair. If that does not work re-install the same on the same 'partition' assuming it to be C by deleting the the windows system files only. While doing so keep the internet on and immediately after the basic version of the OS is installed and the m/c boots-up for the first time, go to the official website and download the latest drivers for every component like toch-pad, keypad, display, audio, etc.(i.e. almost all the drivers)
make sure the mouse and keyboard are in right connections...if you look closely youll see icons next to ports.
try without mouse at first start up ,load windows and use key with windows logo on it to access start and scroll to shutdown tab and restart...plug in the mouse before restart.
if logo tab isnt assigned press ctrl + esc to access start menu.
Found a nice solution at another website: switch off the pc, unplug the power supply cable AND remove battery. Press "on" switch for 20 seconds. Now re-install battery, plug back power supply cable, and switch on. Worked for me (what exactly worked for me I don't know but hey)