Fill water reservoir with 1/3 carafe distilled white vinegar, 2/3 carafe water and hit the self-clean button - it will take about 35 mins to complete. When it is done, it will beep like it normally does when brewing regular coffee. Self-clean light should go off after this. If it doesn't, simply unplug the machine for 20 minutes or longer. The manual is available for your inspection on the Cuisinart website.
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