Well,It's according to actual needs. In general, for small companies, mid lower end is more suitable,. As for large enterprise, the key factor they consider is data security but not price, so high-ended is more suitable for them. Generally, 6500 and 3750 series is used for core layer, 2960 and 2918 series for access layer, 3560 for wireless layer. The Nexus series such as 9000 or 5000 is exclusive for data center. For detail, https://supportforums.cisco.com/
Cisco Nexus 9000 Series
Cisco Nexus 5000 Series
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