Alexis is a given name derived from the Greek word ????? or al?xo, meaning "to help, defend." It was the name of several saints venerated by the Roman Catholic and Eastern Orthodox churches, including Saint Alexis of Rome, and of a Russian tsar, Tsar Alexei Mikhailovich of Russia. It was used as a name for several other members of the ruling house of Russia, including Alexei Nikolaevich, Tsarevich of Russia and Alexei Petrovich, Tsarevich of Russia.
The name was traditionally male, though it has been in use as a girls' name in the United States since at least the 1940s, when actress Alexis Smith (born Gladys Smith) began appearing in movies, and has been among the top 50 most popular names for girls in the United States since 1990. The increase in popularity of the name is sometimes attributed to the 1981 debut of the character Alexis Colby on the American television series Dynasty
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