My acer aspier e1 531 some keys are no working q,t,p,j,1,3,5

Probably, but first I would try cleaning it. Dirt, food and crust gets under the keys and keeps them from working. You can remove the keyboard and wash it, then blow dry with air or let it drain. DO NOT immerse the keyboard in water!! If you soak it, you will have to take it completely apart to dry it out.

Another possibility is the ribbon cable where it connects to the motherboard has built up a bit of corrosion. Disconnect it, wipe with a clean cloth and reinstall. BE CAREFUL. It's easy to break the plastic connector.

If both these fail, replace the keyboard.