How do I get the combo for my safe I have the keys.

I can only give you a very basic answer as you provided NO information on the make and model of your safe. First, some safes allow you to change the combination with the safe open so if you have the keys ...no problem. Some on the other hand require you to know the combo to change the old one like passwords, especially if it is one that allows changes from a factory setting. The best advice is that you should contact the manufacturer on changing the combination, since you have the keys with the key number it should suffice to prove you already have access so they can help you without the required written proof of ownership required to open the safe.