The screws on the derailleur set the positional limits for the derailleur; if your description is accurate and it is always one position behind until the middle gears, I would guess it is not these screws causing the problem, but rather the cable tension is a little to low. There is a typically a knurled knob on the back of the derailleur that can adjust cable tension. Unscrewing it a little will tighten the cable. There may be other adjusters if you follow the cable up to the shifter. Try changing it in small increments (eg 1/8 to 1/4 turns) and go through shifts from high to low before determining if it is helping or not.
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