Here is a link to the user guide:
http://www.giantintl.com/ContentManage/manuals/Moto/MR350-351%20User%20Guide%2012-16-08%20KEM-PK14190-90.pdf You will find the instructions for VOX and iVOX on the bottom of page one, and at the beginning of page 2.
Be certain when plugging in your audio accessory that the radio is turned off. If the radio is left on inadvertently, you would have no control over the VOX settings, it would immediately be in a confused VOX mode.
Also, with most Motorola radios, if VOX begins to occur, turn off the radio, and then re-insert the audio device plug. And in some instances, pressing the PTT on the radio when you are having a VOX occurrence will put the radio back to push-to-talk status.
Best regards.
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