I know this is an old post, but maybe it will help someone in the future. I own the same computer and had this exact problem with Kaspersky Internet Security. Turns out KIS 7 was detecting PS2.SYS as a keylogger. When I blocked the file from loading (per the software’s recommendation), I lost connectivity in both my mouse & keyboard. Eventually, I had to allow the file as an exclusion in order for things to work. Kaspersky says this is a known issue.
When the computer freezes is it just the mouse that freezes? Can you navigate using the keyboard? I would recommend running memtest 86, and prime 95, just to check your memory and processor respectively. How frequent is the freezing? Have you tried stopping a few of your larger processes? Have you installed anything new recently? Also I would try reseating your memory, and maybe having your power supply checked. Doing these things will help limit it down some.
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