I had the same problem. The icon disappeared. Then the 100-2105 error message came up.
The solution on the kodak web site worked for me. http://support.en.kodak.com/app/answers/detail/a_id/1276/kw/ERROR:%20100-2105/selected/true
your computer desktop, select Start > Run.
Type %windir%, then click OK.
Double-click the twain_32 folder.
Right-click the kodak folder, then select Delete.
Insert the KODAK All-in-One Printer Software CD into the CD drive, then go to D: > printer > scanner.
NOTE: The CD is indicated by D: above. The CD drive may be a different letter on your computer.
Double-click aioscannr.msi, then follow the instructions to remove it.
Go to D: > printer > scanner, then double-click aioscannr.msi, and follow the instructions to install the file.
Start Home Center Software.
Select Scan Documents and Pictures.
Scan a document.
If the error continues using a Wi-Fi connection, make sure you select the correct printer in Home Center Software.
If the error continues using a USB connection, see the following section to reinstall the printer.