Whats the condition of your amplifier? New , Used, Old?
You might have a blown channel off your amplifier, this may cause little or no sound. You will have some distortion, crackle sound and then maybe nothing at all. What kind of subs are you running to it? Make sure the subs arent blown and check the voice coils to see that they are not torn off the subs , these are the 2 little silver or copper wires that are connected from the speaker connectors to the sub itself.
Let me know what happens?
Usually answered in minutes!