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The hard drive needs a proper regulated power adapter for the hard drive to work. If the hard drive is a 5.25 inch drive it requires 12 volts and 5 volts power supply. If the hard drive is a 3.5 inch drive it requires a 5 volt power supply.
Check to see if hard drive is fully plugged in/reseat cables/harddrive. see if this fixes the problem if not listen to see if the drive spins up, if it fails to spin up then the hard drive is bad if hard drive spins up but clicks at regular intervals, it is bad Try a different drive cable Try to replace with a known good hard drive, if it still is not detected check the bios to see if the drive controller is enabled.
If the controller is enabled and cannot detect a hard drive the controller may have failed.
I have the same problem with the same enclosure. I found out it is the power supply problem. It worked the first time out of the box. But when the black 12V/5V power supply box heats up, if I turn it off, and on again, my hard drive won't spin up. It had buzz sounds and tried to spin. I think they use a crappy power supply that can't supply enough current during drive spin up when temperature goes up.
My solution is to unplug the whole unit from the wall when you don't use it. That give the crappy power supply time to cool down, so next time when you turn it on, it'll start from cold. This solutoin worked for my 300G Seagate drive. For my smaller WD drive, it doesn't require cold start. I guess it makes sense, as bigger drives require more current to spin up.
If you can open the computer, take out the RAM carefully, clean its base, and put it back gently. Try to reboot, if the machine shows some thing good its OK.
If there is 2 beeps its RAM problem or if it beeps continuasly, its power supply problem.
If you dout RAM, have a new one and check.