I had the same problem. The following solution from 3M support fixed it. We Normally see this problem on laptop computers running Windows XP. There is a power management setting in the Device Manager, which controls the USB Root Hub. Often this setting is selected to "allow the computer to turn off this device to save power". When control of the mouse is needed again, the computer is unable to turn the device back on. To remove this power management feature follow the instructions below. 1. Right click on the "My Computer" Icon on your Windows Desktop 2. Select "Properties" from the Menu 3. Click on the "Hardware" tab in the system properties window 4. Click on the "Device Manager" button 5. Click on the (+) plus sign next to "Universal Serial Bus Controller" in the Device Manager 6. Locate the "USB Root Hub" (Note: there may be more than one, and you will need to change all of them), double-click on the "USB Root Hub" to access the properties windows for that device. 7. Click on the "Power Management" tab 8. Remove the checkmark from the box containing the following option "Allow the computer to turn off this device to save power" 9. Click "ok" 10. Close the Device Manager and all other open Windows Test the Mouse to be sure that the new settings are working. You should now be able to leave the mouse unused without it being turned off by the operation system.
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