Ran out of fuel. replaced has and tried to prime. still wont start.

Pull out the spark plugs from the engine and see if spark comes from the distributor......if not replace distributor...costs around $280

prime it.
try key on 10 time? (on, off, on....)
if the pump dont run keyon,(1/2 cars down) then it must be cranked to prime,or on some cars there is a DLC connector under hood
for pump hotwiring for just this. (oops 2000 dont have it...)
btw : the pump is fuel lubricated and cooled with fuel so you might have fused it (melted it guts out ) running it dry. dont.

id use a pressure gage to see if i could get spec pressure now.
alldata.com has the steps here.

check 12vdc to fuel pump
check all fuses. #13 and #31

Change filter underneath . Relay should be in box under hood drivers side

I’m happy to assist further over the phone at https://www.6ya.com/expert/howard_977676954994c5b2

filling the filters before installing will make priming go more quickly.
once the pump is primed crack open the fuse line at the injector while cranking until you have fuel pulsing out, close it then move on to the next injector.
keep doing this until the engine runs smoothly.
it may start running before all the injectors have been purged so keep clear of all moving parts and a fire extinguisher handy would be a good idea.

Thanks for choosing FixYa and welcome. You probably need to prime the engine. You need to put a little gas into the intake and then try starting it. Check to see if you have a fuel reset button. It may be located in the glove box. If you prime the gas, it should start. You might have to do this a few times before it will catch. If it doesn't, there might be a chance that you have another issue. Make sure you can hear your fuel pump kicking on when you first turn the key. Do this first. Turn the key on for 10 seconds and turn it off for 10 seconds. Do this 5 times and then try to start it. Repeat the process if you have to. This will prime the fuel pump.

I'm assuming that the vehicle started and ran fine before replacing the filter

a couple of things could have happened here...

1.) when replacing the filter you typically have to prime the system by turning the key on and off about 5 times before trying to start. since you just tried to start it without priming you may have created a vapor lock situation. try cracking the line again to vent the system then prime the system and try to start again

2.) you may have either installed the filter backwards or you just got a bad filter

If you ran out of gas, then you will need to perform the following. Turn the key to the on position (do not start). Turn key off. Repeat the process a few more times. Also, have someone help you, for when you turn the key to on, you should be able to hear the fuel pump hum. After a few times, try starting the vehicle. Air has gotten trapped in the fuel injectors. By turning the key a few times, it primes the injectors. If it still will not start, or you cannot hear the fuel pump, then have it checked out. Hope that works. Let me know.

Your fuel pump is in the tank. Turn on the ignition, and listen if you can hear the pump run in the tank. It will only run a few seconds if the engine is not running. You can repeat this several times to prime the fuel injection.

The pressure regulator is bad,it is allowing the fuel to pass threw to the cylinders,replace the regulator,and a new set of goos spark plugs.This is the fuel pressure regulator.

is there a primer valve on the pump? it would unscrew and then pull out if it had one. take a look around the injection pump. but i belive that uses an electric lift pump it should not need to be primed there may be something else going on here.