Installed new vcm and wiring harness last year
Check these three things in the misfiring cylinder: spark, gas, and compression. One of them is wrong or missing. For spark check the spark plug and wire. Make sure you have spark on the plug wire, a strong blue spark. For gas, the fuel/air mixture may be wrong. Does the fuel injector pulse, putting gas into the cylinder? Possibly you may have a leaking injector or a clogged injector.
If gas and spark seem okay, you need to check compression in the cylinder. Low compression will cause a misfire. If compression is 20 or 25% lower than adjacent cylinders, that could be causing a misfire. For example, say numbers 1 and 3 cylinders had about 150 psi compression. 80% of 150 = 120, so if cylinder 2 is 120psi or less, that could be setting the misfire code. Low compression can be caused by valves not seating well, or bad piston rings, bad head gasket- something in the combustion area of the cylinder is losing compression.
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