p1399 for Acura is a random misfire possibly caused by a bad Oxygen sensor.
Cyl. 2 misfire points to either an injector not firing or the spark plug not firing on that cylinder.
The easiest way to test the operation of the fuel injectors is to listen for a clicking sound coming from the injectors while the engine is running. This is accomplished using a mechanic's stethoscope, or a long screwdriver. Place the end of the stethoscope or the screwdriver (tip end, not handle) onto the body of the injector. Place the ear pieces of the stethoscope in your ears, or if using a screwdriver, place your ear on top of the handle. An audible clicking noise should be heard; this is the solenoid operating. If the injector makes this noise, the injector driver circuit and computer are operating as designed. Continue testing all the injectors this way.
Be extremely careful while working on an operating engine, make sure you have no dangling jewelry, extremely loose clothes, power tool cords or other items that might get caught in a moving part of the engine.
All Injectors Clicking
If all the injectors are clicking, but you have determined that the fuel system is the cause of your driveability problem, continue diagnostics. Make sure that you have checked fuel pump pressure as outlined. An easy way to determine a weak or unproductive cylinder is a cylinder drop test. This is accomplished by removing one spark plug wire at a time, and seeing which cylinder causes the least difference in the idle. The one that causes the least change is the weak cylinder.
If the injectors were all clicking and the ignition system is functioning properly, remove the injector of the suspect cylinder and bench test it. This is accomplished by checking for a spray pattern from the injector itself. Install a fuel supply line to the injector (or rail if the injector is left attached to the rail) and momentarily apply 12 volts DC and a ground to the injector itself; a visible fuel spray should appear. If no spray is achieved, replace the injector and check the running condition of the engine.
One or More Injectors are not Clicking
Unplug the fuel injector connector
Probe the two terminals of a fuel injector to check it's resistance
Plug the correct "noid" light directly into the injector harness connector
If the correct "noid" light flashes while the engine is running, the injector driver circuit inside the PCM is working
If one or more injectors are found to be not operating, testing the injector driver circuit and computer can be accomplished using a "noid" light. First, with the engine not running and the ignition key in the OFF
position, remove the connector from the injector you plan to test, then plug the "noid" light tool into the injector connector. Start the engine and the "noid" light should flash, signaling that the injector driver circuit is working. If the "noid" light flashes, but the injector does not click when plugged in, test the injector's resistance.
If the "noid" light does not flash, the injector driver circuit is faulty. Disconnect the negative battery cable. Unplug the "noid" light from the injector connector and also unplug the PCM. Check the harness between the appropriate pins on the harness side of the PCM connector and the injector connector. Resistance should be less than 5.0 ohms; if not, repair the circuit. If resistance is within specifications, the injector driver inside the PCM is faulty and replacement of the PCM will be necessary.
Change the bad fuel injector or computer as necessary.