Hello, Encore Software has released a patch to make Print Shop Deluxe 22 compatible on Windows Vista.
Here is what they say here:
I am looking for the Vista compatibility patch.
This Windows® Vista update will detect and repair The Print Shop® 22 and PrintMaster® 17 applications already installed on your computer. After applying this update The Print Shop® 22 and PrintMaster® 17 will operate normally on computers running Windows® Vista. Update Instructions
1. Click the link located at the bottom of this page.
Note: For Microsoft® Internet Explorer® the File download dialog may appear. Select Save this program to disk and click OK.
2. Choose a location (e.g., the Desktop) and click Save. The download process will begin.
3. When the download is complete, close the Download window.
4. Locate and double-click the Broderbund_Print_Update.exe file that was downloaded to begin installing the update.
5. Follow the onscreen instructions to complete the installation.
Note: Depending on system or user account settings, you may encounter several interruptions during the installation process. If so, please click Continue or Allow in order to proceed.
6. Launch and use The PrintShop® 22 or PrintMaster® 17.Click here to download Broderbund_Print_Update.exe (26.7 MB)