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The only thing that usually causes a scanner error of this type is either a scanner failure or the transport lock. Locate the lock and make sure it is in the unlocked position. Lock and unlock a few times leaving it in the unlocked position then power the scanner off and on again.
My one touch 5800 USB scanner worked great on XP for over a year and then started giving me the unlock the scanner message. I tried different power supplies, reloading software and moving it to a machine running 98SE and nothing improved. I left the cover open and noticed that the lamp was fairly bright at the sides but very dim in the center. I replaced the lamp with one from an old parallel port scanner which was in good shape and it now works perfectly on 98SE. I have not connected it to a XP machine yet.
5800 scanner does not have a physical lock switch. DO NOT attempt to open the
scanner and unlock the hardware. This could be either a hardware failure or
the lock switch on the scanner leaving the switch in the unlocked (open
you are using the correct power supply for your scanner. If you are using a
power supply that has the incorrect DC output, you will get a scanner locked
error message. This flatbed scanners has I believe 100-120V AC input and 12V DC
the power directly to the wall, not a UPS battery back-up, power strip or surge
protector. Power fluctuations from a UPS battery back-up, power strip or surge
protector may be causing this error. If all this fails try reinstalling the
I don't know what your electronics skill level is, but if you feel up to it, try taking the scanner apart and using a jumper wire to close the circuit so that the scanner is permanently unlocked. At least on a scanner this old you do not need to worry about voiding any warranty...
The scanner has a locking device for transport. If it has inadvertently gotten flipped it will cause this issue. Look for the little green or blue tab labeled "Lock" "Unlock" making sure it is unlocked.