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I read your problem description regarding "No Audio" when headset is plugged in and what you've tried was the appropriate ways to troubleshoot and determine this kind of problem.
Trying 3 pairs of known good working headphones and drivers re-installation without resolving this issue clearly tells us that there is a problem with the audio port. It is quite unfortunate that this port is embedded in the system board and the only way to get this resolved is, yes, motherboard replacement.
The next big steps to do is to contact Lenovo Idepad consumer support and discuss this with a technician over the phone. Similarly, you will find more information regarding your system, issues, and possible solutions through their consumer support website :
Lenovo Consumer Support
Thank you so much for using Fixya.
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