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Cannot open AsIO.sys (2) - ASUS Computers & Internet

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Hey there

This might be an installation problem

During a new Windows installation, the Win32 system files read the basic input/output system (BIOS) to see whether the system has initialized all the components. (The RealTek onboard audio is one of those modules.) If you hear no sound after the install, check the system setup to see whether the onboard audio has initialized. If not, then according to your system setup, initialize the audio, reboot the computer into Windows and check the "Multimedia" or "Sound Control" icons in the Control Panel of your Windows operating system.

It could also be a driver conflict

Do not install any other kind of sound drive or enhancer with your Asio driver

Posted on Oct 07, 2010

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