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I would check if your computer is running Anit-spyware like AVG.
I have the same problem, Mcafee is turning it self off because there is another program to take its place.
I have SpySweeper for MSN and Mcafee does the same thing, but before I had Spysweeper, Mcafee worked just fine. So I deleted ALL traces of the former Spysweeper and again Mcafee worked just fine.
There is nothing wrong with Mcafee, it can not compete with others so instead of looking at Anti-spyware code, that most do have Spyware code, so each other would say it spyware.
You can click "Ignore" on the Mcafee, just as long you have another Anti-spyware program running.
Now to fix it you have to go to the reg and remove all codes and prorgams with the any other Anti-spyware that was removed. I use the following to fix all REG codes:
http://www.ccleaner.com and check to see how tight you have your firewall set to also.