First of all boot to the Bios, think its F2 or Del key on that model..
In the advanced screen, checdk to see that USB controllers are enabled for the mouse.
If they are, try plugging another usb peripheral (usb drive or dongle) into the ports, if they ARE recognised, then issue is with the mouse. If they do not register, then issue is with the USB ports. Possibly a damaged USB controller
Goto control panel select mice ect check that the mice is activated you might have to go into bios to enable usb mouse if formentioned dose not work
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