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this is not uncommon. many kvm switches cannot work with those types of wireless mice. the reason for this is due to connection codes. these mice require a connection to secure the use with each computer. you can attempt to do this with your setpoint software. located in C:\Program Files\Logitech\SetPointP you will find the program CONNECT.EXE run this to redo your mouse connection. i will however inform you that even if this works there is a large chance that upon switching to the next pc the mouse wont work and you will need to repeat this process with each pc switch everytime you toggle pcs.
rule of thumb. if the mouse is wireless don't use it with a kvm.
As a wild guess, it sounds like a static discharge MIGHT be affecting the switcher causing it to crash.
Try increasing your humidity to 40% and grounding yourself before touching the keyboard... This is the season for these static electricity problems... get nipped all the time and you MAY not even feel it to be enough to zap the switch.