The most certain means is to remove the battery and then put the phone in a bonfire, but it all depends upon how secure you need to be and whether you want a clean but functional device afterwards and how much expense and effort you want to go to in making your data irretrievable.
Resetting the phone back to factory spec or reformatting /deleting the storage alone does not actually destroy your data.
Please add a comment to give some parameters and you'll get a more relevant answer and I won't have to make generalised comments.
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My HTC G1's Call-in volume is too low, it's really very hard to understand what the caller is...
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My HTC G1's Call-in volume is too low, it's really very hard to understand what the caller is saying! I need HELP!