My Targus PAWM10U wireless mouse doesn't work with Vista Ultimate

Depending on your OS, just use the software provided and then place the batteries in the device and connect it as directed.

First check in laptop that your wireless mouse driver are installed proeprly.
Reinstall drivers then check.

get a wireless one day cheap now

have you tried to change batteries? low battery will cause your mouse not to connect to the receiver.

This was the only link I found:

http://www.bioticaindia.com/pawm10u.html

The driver was posted in June of 2007. About the time Vista was realsed.

I think my mouse is not moving because one usb is missing. I
have trouble find one usb that can help move my mouse.

Click Here to download the User's Manual. It may just be going into sleep mode.

The Targus Wireless Optical Notebook Mouse features an ergonomic design with built-in power management allowing for travel or everyday desktop use. The physical on/off switch, combined with a touch sensor for sleep mode, enable optimized power management capabilities. The thumb-size USB receiver with 90-degree swivel provides flexibility in limited workspace. The mouse features sensitive optical technology for increased accuracy and ease of use.

No you require the targus usb receiver to use it

Are the batteries dead? Try different batteries.

I had this happen to me after reprogramming my tv remote too close to my laptop and mouse. Try resetting the reciever and then the mouse by pushing the reset buttons on each one while they are plugged in ( reciever first, then the mouse ).