Can a healthy pin oak survive removal of 2 large roots in driveway repaving?

check for wood worms or grubs or possible vermin claw marks that are penetrating the bark
the height suggest something standing on the hind legs and sharpening the claws
call in a tree doctor to get a better on the spot diagnosis

You never know that perhaps birds may have made these holes, if tree looks healthy eg Leaves, colour, even Acorns. the Oak is a great tree that can + does survive all sorts of problems, keep an eye open for things which are out of sink. Good luck .

Oak wilt, caused by Ceratocystis fagacearum, is a lethal disease of oak (Quercus sp.). The disease is most serious on members of the red oak family, including red oak, scarlet oak, black oak, pin oak, etc. Members of the white oak family are generally not nearly as susceptible: white oak, swamp white oak, burr oak, etc. The disease is analogous to and potentially as serious as Dutch Elm Disease on American Elm. Both are introduced, exotic diseases caused by vascular wilt fungi; both diseases are transmitted by insects; both diseases can be transmitted through root grafts, and both fungi kill their host plants rather quickly.

To do it right if you don't want to take the tree out is to lift all the pavers in that area and get a back hoe and dig down where the roots are and remove the roots Sawing them out if needed.sin that area. then put a coating of sand and put the pavers back in. That should last for several years . We did that and lasted for several years.

To treat, remove all infected leaves and dropped fruit from the ground. Prune the lower branches from the tree, those that are more than 2 feet from the ground. Then spray with a fungicide such as Agri-Fos orCaptan. Botrytis fungus - Botrytis rot is yet anotherfungal infection which may afflict lemon trees.10 Jan 2016

Lemon Tree Problems: Treating Common Lemon Tree Diseases

https://www.gardeningknowhow.com/edible/.../lemons/common-lemon-tree-diseases.ht.. What is the Treatment for diseases of lemon trees Google Search

get in an arborist( tree doctor) and see what is causing the problem
most likely grubs

Depends on the disease http://extension.psu.edu/pests/plant-diseases/all-fact-sheets/oak-diseases

Most acorns can be eaten, but preparation is required.

http://www.outdoorlife.com/blogs/survivalist/survival-skills-5-ways-eat-acorns

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Take care