There is simple no answer to a question like this. It's just an amp. There are no tweaks except volume. What are the speakers and how much undistorted power can THEY handle?
Amps don't 'run' from 'x' to 'y' ohms. The spec you're viewing tells you how it acts with loads at those values so you can plan accordingly. Since they don't mention distortion values with those wattage numbers the power specs are meaningless.
ANY amp driven beyond its 'clean' power limits will start distorting and THAT will kill speakers if not the amp itself. Audible distortion and excessive heat at the amp are signs of stress. The best sound and performance will be somwhere below that point.
It's not clear what is represented in the "XXX Total Watts Power" statements on page 6. I'm guessing that would be what it DRAWS in wall power so you can plan where to plug it in without tripping a beaker.
Hence, given that no amp converts all of its drawn power into audio power since a lot of heat is created, the actual usable audio output wattage would be somewhere closer to maybe 40% of the total divided by how many speakers are driven. No reputable manufacturer specs an amp at 'x watts time y channels'. It's "PER CHANNEL all channels driven" that makes any sense for comparison.
If a car can go 150 miles per hour and has 4 wheels is that 4 x 150 for output if it had only one wheel?