Flickering mouse flickers and disappears when a game or movie is being play why and how do i fix this plz??

Flickering can be adjusted. If you wish to get some details; visit the site linked here. Pull up older posts. http://electronicshelponline.blogspot.com/

I don't know about it being a virus, but if it is,.. Have you updated your virus definitions and the rest of your Anti-virus, Anti-spyware progrms and actually run them lately?
Some people hardly ever update and/or run their programs.
You might also try updating your mouse drivers.
May I suggest, VersionTracker Pro $29.95
http://www.versiontracker.com/windows/
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go into your dispay menu and adjust the response 50-60hrz or if your tv is capped at 1080i then drop the ps3 to 720p and that will smooth it out alittle too as the interlaced picture is alittle choppy apposed to progressive picures and finally sometimes they just do it no rhyme or reason to it so dont go crazy about this ok :)

I wasplaying a game and the lights flickered off and on and now it wont play any movies or games. What can i do to fix this problem.

Is could be your TV and not the PS3. When the resolution of the screen changes, you TV will flicker to adjust to the new resolution. My TV flickers in a similar way when playing games of lower resolution than my HDTV.

Does it do this with all Blu-Ray movies?
Have you tried a different HDMI cable?

It seems to me that the memory for your graphics card is not enough to play the game .64MB is quite small for that sort of game. If you check the mininum requirements for your game .

use another Tv.

Since your mouse works fine other than in the game can I suggest you instal the latest driver combo from ATI. Just because the card has PowerColor's name, it's still an ATI chip.
So in this order, update windows. You'll need .Net framwork 2.0,
do not skip lower version & install .Net framwork one at a time restarting when requested. Install directX 9.0c from here:
http://www.microsoft.com/downloads/Browse.aspx?displaylang=en&categoryid=2
Uninstall any other versions currently installed on your system.
If for what ever reason the uninstall fails, download and run ATI's uninstaller "cat-uninstaller.exe" to clean your system from here:
http://searchna.ati.com/promosearch/?site=us-en&la=en&qt=cat-uninstaller&selectsite=ATI&sp_a=sp10039240&sp_p=all&sp-x-1=col&sp_f=ISO-8859-1&sp_q=cat-uninstaller&Search.x=9&Search.y=8
You’ll find lots of cool features within the Catalyst Control Center.

Don't forget to vote!

When the TV is flickering, do you notice any noise in the audio? If so, it could be a loose connection inside the set or a High voltage transformer going bad. Does it constantly flicker or come and go. If the latter, can you slap the side of the TV or jar it to get the problem to come and go? If so, it is likely a bad connection inside the set. I'm assuming that when you were playing the movie that you used the A/V input jacks rather than using the tuner on channel 3. Otherwise the tuner could have bad connections or bad grounds inside. A repair shop will most likely have to fix this problem. If the set was over 9 years old however, I'd upgrade to a new HDTV set.