When i hit a bump in the road with my chrysler pacifica it sounds like the passenger side wheel is goin to fall off.

Check the lug nuts..
Could be a bad front end bushing or could be a bad ball joint.
Check for re-calls too..
Jack up the front end (be safe) leaving the pssngr tire hanging free.. Move tire left to right.. You should find out what is going on..

Jack up that wheel and look at it, shake it etc. Many times a noise like that can come from the strut top bearing as well.. Bounce the car and put your hand on it...If you feel slight bang there it will be louder with the weight of the car jouncing it on bumps.

Have a mechanic jack up the front of the car and check the suspension for loosness if none is detected, it could be a faulty upper strut mount