We have a zvox z base 580 sound system it just stopped working we changed the batteries in the remote and checked all wires and nothing

Check the remote controls, for its infrared emission. Check it with fresh batteries. Check it by pressing all the keys. You can detect the presence of infra-red emission from the remote control, using a cell-phone camera. If you wish to get more details about how to check a remote control, please visit this site. One among the posts has details about it. In some cases, the remote control might need to clean.
https://electronicshelponline.blogspot.com/
https://homenol.blogspot.com/
https://remotesearch.blogspot.com/
Search the site by type in this key phrase "how to test a remote control "in the "search box at the top right of the display window of the Homepage" to get the related post quickly.
https://youtu.be/wUpnETSm6_k
https://www.youtube.com/watch?v=jsSCNCW3IbQ [open and clean]
https://www.youtube.com/watch?v=Qp-l1uh-5gE [open and clean]

They to check the menu of the TV is there is any option to activate the Digital out or is there is any setting which allow you make a selection between internal speaker or external speaker. if its there the make the setting as external speaker .
If you wish to get some details; check the site linked here. Pull up older posts.

http://electro-medical.blogspot.com/

Universal remotes only work when the correct code is entered into it. Some codes for the same make will work other models, but things are either missing or function differently. You need to find the correct code and try the functions using it. If everything is OK then it should be fine, if not try another code.

However the best remote for the job is the original that came with the equipment. Unless you have paid out a lot of money for a universal remote, you might never get the same responses as an original remote.

I am the same boat. Just bought a bigger tv and my zvox doesNOT work now

Batteries could be bad, circuit board in the remote may be shot and try cleaning the infrared light on the remote and TV. If none of that works order a new remote or get an all in one, just make sure it has the programmable code for your TV

test the speaker with a known good source (cell phone, other stereo, etc) and see if that works. You have to pinpoint the reason why it's not working, could be power, could be signal source, could be connection quality, could be poor internal connection or solder/joint on a wire

You could have fried something through a power surge or a connection came loose. Check all wiring and see if the speakers are connected, try different audio signals to see if that helps

Place the unit in learn mode: http://www.zvoxaudio.com/mas_assets/theme/zvoxnew/documents/ZVOX580_LearnRemote_Guide.pdf

What type of cable are you using to connect your ZVOX system? Are you connecting your system directly to your TV? In order to solve your issue as quickly as possible I would encourage you to call our toll free number.
(866) 367-9869 We can troubleshoot over the phone and get you up and running in no time. Thanks.

- Joe

ZVOX Audio - Great Sound, Made Simple
www.zvoxaudio.com
866-367-9869