Rank: Wiz
Rating: 85%, 935 votes
If you mean that your Windows desktop does not fill your screen, use the monitor screens menu to adjust the settings and make it fit the screen.
If you mean the windows you view within your desktop do not expand to the edge of the screen, click the middle icon in the top right corner - between the _ and the x this should maximise the windows.
For further info you will need to post more information about what equipment makes and models you are using. May also be better if you posted your problem in the correct section. This issue has little to do with speakers me thinks.
Let us know how you get on.