I would start addressing the issue by checking the 'properties' setting when printing and making sure that the right type of paper is selected. You can also adjust the quality of printing at this stage and see if setting the quality to a high level will help.
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Hello, first unplug the the printer and take out the cartridges, first dab them on a wet paper towel until the ink start flowing, then take a q-tip dipped in alcohol and where u insert the cartridges, clean the print heads, replace the cartridges and power up. If that doesn't help it you have bad cartridges.
The 5250 auto adjusts the sharpening and contrast, as well making black point adjustments. Those adjustments cannot be turned off so you are stuck with them. Whatever changes you make in a photo editing program will be worthless because the changes will ALWAYS be undone by the 5250.
What program are you using to print out photos?
Try to take the ink cartridge out and put it back in.
Go to this link, instructions on how to replace ink cartridges http://files.support.epson.com/pdf/cx66__/cx66__pg.pdf
And then try to print. If you have the same problem, try to use another program that you can print pictures from.
It might be ok but in general it is not suggested to refill your ink cartridges. Third party ink is never as good, may be to think or too runny then the Canon ink. It would definitely shorten the life of your printer. Look for high capacity print cartridges if you're looking to save a little money.
Some of Epson's ink have inconsistent quality. Some batches have runny ink. Nozzle cleaning and print head alignments don't help at all, if they didn't make it worse in the first place. I've experienced problems like yours several times as well. Here's what I did that worked for my Epson 960. Move the printer to a really dry place. Take out all the ink and let the printer sit and dry for a few days and then change all ink cartridges. Make sure you buy newly created ink. All Epson ink come with born-on dating so find the ones with the most recent dates and make sure the whole batch is produced at around the same time to ensure color consistency. Plug them in and try it out. If the problem remains, you may need to bring the printer in for repairs.