Question about HP PhotoSmart C4385 All-in-One Printer

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HP photosmart C4385 scanning problem

I'm having a major problem with my scanning. Generally it will work through the HP Solution Center, but with that I've got to preview, crop, and scan rather than just scan quickly, which is what I was doing with Photosmart 2.5. Photosmart is much easier and quicker to use.

So when it's working, I click scan on the printer and it asks which computer to scan to, but 90% of the time now when I click scan it just starts scanning and says "USB or Wireless not connected". When it's doing this, it won't work while plugged in either. The odd thing is that regardless of whether the scanner is working or not, the printing always works wirelessly.

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  • BrianLink197 Dec 31, 2008

    I have the exact same problem. I cannot scan at all, the screen on the printer says "USB or wireless not connected." But the thing is - I can print perfectly over the wireless network. I ran a connection test and everything passed, no problems, yet I still can't scan at all.

  • Anonymous Jan 08, 2009

    i have a mac and the same exact problem...its saying that the usb isnt connected but it is...i need help

  • Anonymous Jan 12, 2009

    it keeps saying usb not connected WTF is going on?!!!!!!!!!!!!!!

  • Willii Jan 21, 2009

    Have the same problem! Printing works wireless, but when trying to scan got the same message. I try it with a cable, but even this doesn´t work.

  • oodoot Feb 15, 2009

    Bandana_gyrl I've tried to follow your instructions in step 2 but they seem to be for a different operating system to your instructions so I can't find any setup assistants or wizards for the scanner. Can you offer any further info for Windows Vista platform please? Would be great as this is sounding very promising!

  • Anonymous Mar 31, 2009


  • cvpatree Apr 06, 2009

    HP4385 is connected via a cable and when I try to scan it says
    "USB or wireless not connected". I'm really frustrated....

  • Anonymous May 18, 2009

    Prints wirelessly fine, won't scan plugged or wirelessly. mac.

  • Anonymous May 25, 2009

    Same as others, I can print all day long, but when I attempt to scan, I get the "usb or wireless not connected" error message.



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Ok - the reason this error pops up is because there is a software issue going on. If the software is correctly installed you will see options for where the scan will go in the computer.
Having said that there are several things that can cause a problem between the printer and the software;
1) You are connecting the printer by USB to router - you may print but will never be able to scan as this is not a networkable printer. Connect it directly to your computer and recomplete the setup portion to configure the scanner.
2) You have not finished the setup. At the end of the installer you can setup the scanner but if you skipped this step you will have to redo it in order for it to connect. Click on the device manager in your dock and then next to information and settings there will be a little wheel. Click on the wheel and go to setup assistant. Complete the assistant and try to scan.
3) The printer is not grabbing the new software options - leave the printer turned on but unplug the power cord and wait for 30 seconds. Plug printer back in - when you do this it should initialize and will look to the mac for changes and the options should load.
4) Software missing - You MUST have the software for the printer installed for scanning function. Adobe and other programs cannot replace it - it has to be installed.
5) Software is corrupted. Uninstall the software (uninstaller is under applications in the HP folder) and then download ( and install the most recent full feature software and drivers for your operating system.
6) If all these steps fail you may have an issue with your computer and it's TWAIN drivers.

Posted on Jan 17, 2009

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I could only figure out a work-around Go to Control Panel>Scanners and Cameras> Click on the device e.g. HP Photosmart xxxx

Posted on Mar 20, 2009

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Browser based updates such as Adobe Flash are overwriting certain system files that the HP Scan depends on. The day your SCAN operation failed, you downloaded some update from your browser. The HP install is flawed for re-installs and there is a good chance this procedure will fail - I restored from GHOST.

Posted on Sep 12, 2010

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Don't try to scan from the printer control panel.  You need to launch the "HP Photo and Imaging Director" from your computer.  I have HP Photo & Imaging SoftwareVersion 2.0 installed which I believe was obtained from the HP site for the C4385.

The scan function works fine if you use this software.

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I have new Hp photosmart C4385 all in one scanner, printer, copies. The printer was initially onstalled. Working w/ wireless HP pavillion. It print & copies fine. Scan does not work. When I enter...

I had a similar problem recently... You have to actually install the scanner software. You probably only installed the print drivers, but not the scanner software. If you don't have the CD handy, go to In step one select "Download drivers and software (and firmware)". In step 2 enter your model number (photosmart C4385) and then press "go". It will lead you to a page to select your operating system. Follow that link to download the entire CD (large file).

When you are installing the software, make sure to install the scanner software too.

John Lox

Apr 14, 2008 | Computers & Internet

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