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you can open it given that u know how to take it out and put it back without breaking it... and also i would say that u dont have to do it... it wont make much changes and also what will u clean inside a mouse??? there wont be much dust inside... probably u can clean the bottom part... for easy movement... and also if u open the mouse, the warranty (if u have one) will be tampered...
so all together i would suggest u not to open it.... :)
You plug in the wireless antenna (probably a USB stick) and then turn on the mouse (assuming the batteries are fully charged). Then turn the mouse over and make sure it's turned on and press the "connect" button.
The screws are under the back 2 feet and under the label. The label you can just feel for the holes and press thru with a screw driver. For the 2 feet, you can either peel them off (and buy replacements or re-glue the old ones back on), or just press the screw driver thru the center of the feet
Is this a Microsoft Wireless 5000 Mouse? The battery plate should be on the bottom of the mouse to take off to put in the batteries, similiar to a TV remote contoller. And it can be latched pretty tight.
Included a Youtube video of someone taking the battery out of his mouse.