I have a USB Microsoft optical mouse, a PS/2 keyboard, and a Foxconn 6100K8MA-RS motherboard running Windows XP Pro SP3. I'm trying to free up a USB port by moving my mouse to a PS/2 port. My USB mouse works fine in the USB port; it doesn't work when I plug it into the mouse PS/2 port via a USB-to-PS/2 connector. I've tried two of those connectors and neither works. I'm pretty sure there's no bent/broken pins involved. The USB mouse has worked in PS/2 ports before. The PS/2 keyboard works fine in the PS/2 keyboard port. I'm not sure what else to try.
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If you are talking about a PS/2 mouse and keyboard (round plug with 6 pins), the green port (top one if you have the computer sitting on its side) is for a mouse. The other one (could be orange) closest to the case is for the keyboard. If you are talking about USB ports, it doesn't matter at all.
click start control panel view devices and printers you should see your mouse right click mouse you could open it and then select configuremy mouse or select settings then hardware make sure you have the correct mouse selected also right click on the mouse select properties to make sure you have the correct mouse right click on mouse you can troubleshoot this will activate the troubleshooting for you hope this will help
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Besides the obvious checking with your device manager, you can download a port test kit HERE. That will be able to test if it's working. The other thing you can do is switch the keyboard into the mouse port and the mouse into the keyboard port. You should get some errors, if not, one of them will work and the other won't. Hopefully, you'll get the keyboard in the mouse port to work, so you know the port is working. Also, if you have any other PS2 devices that you can test it with.
Good Luck and don't forget to leave a rating based on my solution.
Often times this happens when using a USB keyboard / Mouse.
Or when using a USB keyboard through a PS/2 Converter.
Try using a PS/2 Keyboard if available (Small Round connector with a small amount of pins, similar to a S-Video connector.)
Also. Access your BIOS settings and assure that you have Legacy USB keyboard support. Depending on your computer the BIOS / Setup Menu / Options Menu/ Etc. can be accessed by pressing the following key during boot: F1 F2 ESC DEL F12
Let us know your setup(KB and Mouse Port type), and if you have any other issues.
On the PS/2 mouse, chances are that the surface mounted fusible link/resistor supplying the +5VDC is open. It is normally very near the PS/2 port and marked  or labeled F???. This can be verified by measuring the absence/presence of +5 at pin 4 of the connector. In some cases, it is the I/O chip that gets damaged.
Re "only two(2)USB port" aside from the 2 rear USB ports, the Asus CUV4X-C has another pair of USB connectors that are normally connected to the front panel of the casing. It is located very near the motherboard battery.
Re "...prompting...high speed USB port...", normally by updating your OS (say XP to SP2) or downloading/installing latest VIA 4 in 1 Drivers should make your USB 2.0 compatible.
Hope this be of some help/idea. Pls post back how things turned up or should you need further information.
Good luck and kind regards.