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Turn the computer off, and disconnect the AC power.
If the motherboard has an "integrated" video-adapter, connect one monitor to its VGA port, and connect another monitor to the VGA port on the add-in video-card, and turn the computer on, and watch both monitors, to see which one becomes "primary" and which one becomes the "secondary" monitor.
Reboot, and enter BIOS SETUP, and "disable" the "onboard" video-adapter, then "save and exit" and reboot. Now, which monitor stays "dark" and which monitor is "primary" ???
Lets tackle the monitor first: A no signal message indicates one of two things;
The video card isn't properly seated; (if the video card is on board skip to next step) just moving the video cable on the monitor to unplug it is enough to unseat the video card. Open the tower again and make sure the card is firmly in place.
If the video is onboard, the plug may not be firmly in place. Check the screws that hold the plug in place and see if they are turned as far as they will go; there's a chance the plug is only partially making contact giving you the no signal message
As far as the mouse goes, the only reason the machine won't recognize the mouse would be a faulty connection in the USB port. Assuming no damage was done while blowing the dust out, double check the USB port, maybe even changing ports to see if the mouse comes back. If your machine is anything like mine, space behind the tower can get kinda cramped and just putting it back into place and reconnecting the power cord can pull just enough on the lines to pull a line just enough to disrupt your connection.
Hope this answers your questions. Best of luck. Greg
No. You need to look at the model of your board properly and look up that manual online if you don't have it with you; at least look at other boards by the same maker! Better connect a muted speaker though, because once you do connect it it will beep out a BIOS beep code for you to look up. Seriously, if it's in pieces for other reason than that it's broken, what do you expect of people?
Try a few things for me OK? From what you typed, turned on the psu "the toggle switch on the psu", pc seemed to be starting up. I need you to keep the toggle switch on the power supply in the on position. Press and hold the start button on the PC case to shut it down. Give it a few seconds & power up by pressing the power switch on the case. Notice a differance? Next, unplug everything connected to the pc expect the monitor, mouse & keyboard. Try to boot. Still no? Remove the side of the case exposing the board. Turn the psu off by flipping the toggle switch on the psu, wait till the green light on the board goes out. Grab the Mb ( I know it's tight in there) and see if you can move the board in any direction. Not loose? Re-check all data & power connections for a solid connect. Re-check your case to Mb connections. Also check the PSU, there is a red slide switch it should be set to 115v. Post your findings..