I have entered the serial number given me without success to activate

You have to purchase the product software. Then you will be given the activation code. You only have to enter this code once. Then you can use this software again without having to enter the activation code.

The key might be on the manual or the box if its not on the cd.
Dragon Naturally Speaking is a software program designed by Nuance Communications that enables a user to speak instead of type to both transcribe information and control his computer. This is beneficial if you don't like typing or physically cannot do it.
The software requires a headset microphone to work and some configuration to get started. To continue using Dragon Naturally Speaking, you must register it or it disables itself.
Activation is done online and requires a product serial number.
The location of the serial number varies depending on the software version, but it should be located on the box, CD case or manual.

Start Dragon Naturally Speaking.
When it completes the loading process, click "Activate Now" when prompted and then click "Activate Automatically."
Enter the serial number in the space provided and click "Generate Activation Key."
Copy the activation key into the activation text box and click "OK" to activate Dragon Naturally Speaking.
How to activate Dragon NaturallySpeaking without an Internet connection
http://www.spectronicsinoz.com/article/how-to-activate-dragon-naturallyspeaking-without-an-internet-connection

Hi, the Serial Key for the Speed My PC is :

SP-FCLF4-MSG66-M2N27-WBY7S-5DGPL-LNPP2

Please enter the Serial Key manually rather than copy-pasting. This should activate the Speedup My PC successfully.

Please do not update the existing version of the Speedup My PC Software this may deactivate the existing activation.

Hey Michael,
You can enter the serial number under the Help menu, and then clicking "Activate." Make sure it is a verified serial number and you should be good to go!
Let me know if you were able to do it successfully. -virjog

Occasionally some Windows Vista user may need to activate his or her copy of Windows Vista operating system through phone activation, such as in situation where the computer is offline without Internet access. Other possible reason to use phone to activate instead of automatic online activation is failure or facing problem to activate Vista online, and user have to fallback to alternative.

For most users, activation process normally starts with attempt to activate Vista online. Online activation is simple and effective way to activate the copy of installed Vista, and when it fails or cannot activate successfully, then user can opt to activate by phone. If you want to skip and bypass online activation and go straight to activate Vista or Windows 7 by phone (i.e. in the case of offline PC with no Internet connection, do these steps:

1. Click on Start Menu.
2. Type slui.exe 4 into Start Search, and then press Enter.
3. Go to step 10.

Normal activation procedures for Windows Vista, including fallback on phone activation:

1. Click on Start Menu.
2. Right click on Computer and then click Properties, or open the Control Panel -> System and Maintenance -> System icon.
3. Scroll down to the Windows activation section and click on the Activate Windows now link.
4. Click on Activate Windows online now. Note: If you have not entered a product key during installation, the wizard will ask for a genuine serial key. If you uncertain of the serial number key used, or want to change the key used, click on Change product key link.
   And, this step must fails in order to go to phone activation.
   
5. If the online activation process, user can continue to attempt to activate using automated phone system by clicking on Use the automated phone system to activate option.
6. Select your location and click on Next button when prompt to find available phone numbers for activation.
7. Click Continue if prompted with UAC dialog box, except for those who had disabled UAC.
8. A local phone number or nearest telephone number will be displayed on screen, together with a set of Installation ID (54 numbers in total - 6 numbers in 9 groups) generated by Windows.
9. Call the activation phone number.
10. The call will be answered by automated voice response (AVR) system, that asked caller to speak, or if voice recognition failed, press the phone button to enter the Installation ID listed behind "Step 2?. The numbers needed to enter is a lot (54). If you want simpler way to do it, just speak and enter anything to let automated service fails, and then wait for the call to transfer to activation operator (a real human). Sometimes, if for some reason the Installation ID entered is not accepted by the AVR, your call may be transferred to human operator too. Note: The human operator may ask for the reason that causes requirement of reactivation or activation of Vista. Just tell the truth, e.g. hardware upgrade, transferring to new PC (for non-OEM edition only) and etc.
    
11. No matter who you talk to (machine or human CSO), a set of Confirmation ID numbers which consists of 48 digits (6 numbers in 8 groups) will be given if Microsoft believes that your copy of Windows Vista is genuine and legitimate. Write down the Confirmation ID.
12. Back to Windows Vista, type in the Confirmation ID given by the phone system into the wizard boxes after the "Step 3?, and then click on Next button.
13. The activation should be successfully done with Activation was successful window appears. Click on Close button to quit.

I’m happy to help further over the phone at https://www.6ya.com/expert/jeremy_69f3cc28d95bf514

>To install illustrator use key: 1034-1340-5003-7121-5803-5483

>Then chose the activate by telephone option and was given the request code:
5059 - 0493 - 2899 - 9049 - 2737 - 6085 - 6054

>The generated response code is: 9657 0937 4948 4768 4053
this doesn't activate illustrator...

>However it successfully activates illustrator if you reverse the order of the sequence of numbers in the generated response code....
i.e.
4053 4768 4948 0937 9657

Please vote if this helps.

You may have purchased a pirated copy of the software. You need to contact Adobe, and they will help you to determine the validity of your software purchase, and get you a new serial number or re-activate your current one.

If you go to Adobe Customer Support: CLICK HERE
... you can select the pop-up which offers Live Chat Support. They are very thorough and very helpful.

you will have to call Microsoft to reactivate.

You must activate your Microsoft product to confirm that each copy of the product is not installed on more than the limited number of computers that is indicated in the software end user license agreement (EULA). The activation process can be performed by using the telephone, a modem, or the Internet. None of the information that is collected during activation will be used to personally identify you.

To activate your product over the telephone • • Windows activation: (888) 571-2048 •