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Quantaray has made several different 70-300mm lenses so I'm not sure exactly which one you have. However, if the lens doesn't have a AF/M switch it's no big deal. Assuming it's an autofocus lens, it's always on. If you want to switch to manual focus, flip the switch on the camera body.
If it's an older manual-focus Quantaray lens then the question is moot.
Yes, with caveats. The autofocus won't work on D40/D60/D3000/D5000. The metering may not work in all modes on all cameras. Since you didn't specify which camera, I can't give you a better answer than that.
I have 30-year-old Nikon lenses working fine on my D90, but without metering. And the old lenses date before the invention of autofocus.
That's good info. The trouble is that Quantaray makes lenses for different bodies. Your lens could be made for Minolta, Nikon, Canon or other. You may be able to find a universal adapter but first you need to know what mount that lens was originally made for. I recommend either taking the lens to a camera store or calling Quantaray to see if they can look up the mount using the serial number.
Turn the aperture ring on the lens to its smallest aperture (largest f/number) and lock it there if it has a lock. You control the aperture through the command dial on the camera body, not the aperture ring on the lens.