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Try to install this link --http://canoscan-4400f.software.informer.com/
and then restart the scanner also check the settings in you computer as well. i dont dont have information about your os. so i can help you so much but yeah let me know if you have any further questions or concerns.
This is most likely only happening when attempting to scan through the CanoScan Toolbox. You can scan directly through ArcSoft PhotoStudio which came with the scanner. However, the error through Toolbox is likely caused by some limitation or restriction in the computer, possibly permissions of some sort. You may try deleting temp files from the Temp folder on the hard drive.
Hi there, yes I did everything per your instructions, Toolbox is installed and it still says, "release the lock switch, detach I/F cable and reconnect. Scanner driver will be closed" and then after clicking on that it says "Unable to open TWAIN source. Please check connection then restart toolbox" I have been to the Canon site and downloaded driver sites and it says everything is working. but when I go to scan it comes up with the boxes I said before. Quite lost at the moment? Thanks Maureen. PS I have unstalled and reinstalled